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KMID : 0869620070240040302
Journal of Korean Society of Hospital Pharmacists
2007 Volume.24 No. 4 p.302 ~ p.311
A Comparison of Early Enteral Nutrition and Total Parenteral Nutrition after Total Gastrectomy
Kwon Hee

Son Eun-Sun
Ko Jong-Hee
Ahn Ji-Hyune
Song Seung-Eun
Lee Eun-Joo
Lee Ho-Sun
Cho Mi-Hwa
Kang Jeong-Ae
Shin Hye-Sun
Yoon Seok-Jun
Yoon Ho-Young
Kim Choong-Bai
Abstract
This study was aim to compare nutritional parameter, immune competency, and types of complication between early enteral nutrition (EN) and total parenteral nutrition (TPN) after total gastrectomy. Patients were prospectively randomized to receive early EN by nasoenteral tube (n=17) or TPN via central venous catheter (n=16) after total gastrectomy in Yonsei University Health System from March 2006 to July 2007. The nutritional goals were 25kcal/kg/day for total daily calories and 1.5g/kg/day for total daily protein. No significant differences were found between the two groups regarding nutritional parameters and length of stay. However, AST/ALT level on post operating day (POD) 7 was slightly higher in the TPN group compared to the early EN group. There were no infectious complications in either group. Complications encountered in the early EN group were GI complications such as nausea, vomiting, abdominal distension and increased AST/ALT levels whereas in the TPN group, total bilirubin and ASL/ALT elevations. Considering the fact that both groups showed small decrease in weight, active nutritional support is essential in patients with total gastrectomy. There were no statistically significant differences between early EN and TPN group following total gastrectomy in terms of nutritional parameters and immune competency. Based on this result, both early EN and TPN seem to be appropriate in supplying nutrition after total gastrectomy.
KEYWORD
Total gastrectomy, Early enteral nutrition (EN), Total parenteral nutrition (TPN)
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